Studies On Quality Control Technology Of Mineral Chinese Medicine Chloriti Lapis

Chloriti Lapis used in Chinese medicine for the clinical commonly used mineral medicine,the application history is glorious.At present,the mineral used in Chinese medicine quality specification is sketchy,the market variety origin is chaotic.Access to Projects in the National Science&Technology Pillar Program during the11th Five-Year Plan Period of China.(Grant No.2006BAI55B02) and Program sponsored for scientific innovation research of University postgraduate in Jangsu province,China.(Grant No.CX09B-282Z) funding,to better control the quality of Chloriti Lapis,the subject based origin identification, analysis techniques,processing technology and other means of quality control study,to expect a scientific and feasible quality control techniques and quality control standards.Quality control and control technical means of mineral drugs to the status quo,and the literature about Chloriti Lapis had been systematically studied.The ancient literature focus on the historical writings of ancient medical books, mainly mineral species,clinical application,history of the processing method,processing mechanism and the original intent.Through the modern domestic and foreign literature research,chemical composition,clinical practice,efficacy and toxicology,quality control methods of Chloriti Lapis were summarized.In this foundation,quality control methods of Chloriti Lapis were studied by modern instrumentation equipments and statistical analysis methods.Through research,main access to the quality control technology and parameters of processing of Chloriti Lapis,and quality control standards were further established.For the first time to Chloriti Lapis,FTIR and XRD Fourier fingerprints were established,TA authentication method was established,25kinds of inorganic elements were determined by ICP-MS,the feature recognition chart of20kinds of inorganic elements was established.Carried on systematically preparing processing research and established the best preparing processing method. Comparative analysis of the processed products and raw materials in the FTIR spectrum,the XRD Fourier spectrum,and elements content difference,the difference of the water-soluble out rate.In addition,polarizing microscopes,TA,XRD,FTIR,AFS,ICP-MS,electron microprobe and preparing processing research ideas would guiding significance to the study of the drug for other minerals.