Studies On Bioactive Compounds And Quality Evaluation Of Tribulus Terrestris L.

Tribulus terrestris L. are a famous traditional Chinese medicine and has been used for over hundreds years. It can restore the depressed liver for the treatment of fullness in the chest and mastits and also used to dispel the wind and clear the eyes for the treatment of an acute conjunctivitis, headache and vertigo. It has been used for a variety of liver, kidney, dizziness, psoriasis, eczema, premature ejaculation and cardiovascular diseases. The Greeks used the medicinal herb Tribulus terrestris L.as a diuretic and a mood-enhancer. Eastern Indians used it as a diuretic, antiseptic, and anti-inflammatory. The people of Bulgaria used Tribulus terrestris L.as a sex enhancer and to treat infertility.Tribulus terrestris L.is used in various herbal formulas to treat headaches eye problems such as itching, conjunctivitis and weak vision, pain relief, enhancement of the immune system, improved mood and sense of well-being, cholesterol reduction, and relief of premenstrual (PMS), menopausal symptoms in women, and nervousness, making it a great menopause herb. In women, hormonal imbalances can lead to the typical unpleasant symptoms associated with PMS and menopause. It is also used to treat high blood pressure and rib pain. Recently, eastern European athletes and strength champions have used it as well. Many athletes and bodybuilders have found Tribulus terrestris L. a safe and natural alternative to anabolic steroids.Tribulus terrestris L.contains three groups of active physiochemicals:Dioscin, protodioscin, diosgenin and similar, these substances have effect on sexual performance and may treat various sexual disorders, they regulate sexual energy level and strength by increasing the percentage of free testosterone level for men and they effect pregnenolone, progesterone and estrogen. The hormone balancing effects of Bulgarian Tribulus terrestris L.for women makes this herb suitable for premenstrual syndrome and menopausal syndrome. Sterols like betasitosterols or stigma. These substances protect the prostate from swelling and in combination with the steroidal saponins, protect the prostate from cancer. Steroidal saponins currently referred to as steroidal saponins. These steroidal saponins effect the complete immune system. They have been demonstrated to possess anti-bacterial and anti-viral effects. Bulgarian Tribulus terrestris L.may be used internally and externally to treat herpes, and virus infections such as influenza and the common cold.In this studies, firstly, in order to do more studying on Tribulus terrestris L., we investigated its water-solubility constituents by using UV-spectral method to determine the content of the total saponins and HPLC method to to determine the total flavonoid glycosides. Methods studying results shows that the two methods were convenient, rapid and accurate, and could be used for quality control of quality of Tribulus terrestris L. According these two methods, we took study on Tribulus terrestris L. The 3 samples results show that the total Saponins in Tribulus terrestris L. are 1.55,1.59,1.67, average is 1.60%, and the total flavonoid glycosides are0.97, 1.12,1.23, average 1.11%. The resins are more proper used to exacting water-solubility constituents in herbs these days. We compared nine kinds of different resin. AB-8, performed a good reputation, was being adapted. The optimum condition of using AB-8 were concentration: 0.5g/mL , velocity of flow:8/1000BV/min, ratio of diameter and high: 1: 40, and were development by using orthogonal tests.Secondly, We investigated Tribulus terrestris L.chemical constituents of the fruits of Tribulus terrestris L by using SiO₂, polyamide, gel, LH-20. Chemical constituents from Tribulus terrestris L. 20compounds were isolated from it and 17 of them were structurally elucidated. With the compounds name: terrestrisA(TTl); hecogenin-3-O-.(3-D-xylopyransyl(1-2)-[β-D-glucopyranosyl...