Study On The Chemical Consitituents Of Helianthus Annuus, Vernonia Cumingiana And Eritrichium Rupestre

Helianthus annuus L, is widely planted all over the world, and it is not only a economically edible plant but also a worthy of studying and developing medicinal plant. The face chunk, stem, leaf and seed of it have medicinal value. The study on the chemical constituents of sunflower was done in early twenty century, and mainly focused on the seed and the aerial part in the growing season. For its multiple medicinal function and cheap character, we did chemical and pharmaceutical research on grown sunflower in order to change wastes into valuables and make full use of rich natural resources to contribute to the human health.Systematic isolation of the acetone extract of the aerial of H. annuus on the basis of modern chromatography and methods gave twenty five compounds, and they were identified by the spectroscopic analysis (Including IR, ¹H NMR, ¹³C NMR, HMQC, HMBC, NOESY, ROESY, EI-MS, FAB-MS, HREIMS and X-ray diffraction analysis ). Among of them, six were new and six were isolated from the genus Helianthus for the first time.New compounds were ent-kaurane-2β, 16β-diol (HA1), ent- kaurane-15α, 16α-epoxy-17β-al-19-oic acid (HA2), N-phenylethyl-tetracosanamide (HA22) (2S, 3S, 4R, 2'R, 8E) -2- [(2'-hydroxy)- hexadecaneamideyl]-8-octadecene-1, 3, 4-triol- 1-O-glupyranoside) (HA23), (2S, 3S, 4R, 2'R, 10E) -2-[( 2'-hydroxy) docosaneamideyl]-10-eicosene-1, 3,4-triol (HA24), (2S, 3S, 4R, 2'R, 3'R, 10E) -2-[(2', 3'- dihydroxy)-docosaneamideyl]-10-eicosene-1, 3, 4-triol ( HA25 ). Other known compounds were...