Clinical And Experimental Study On Endometriosis By The Method Of "Fu Zheng Qu Yu"

Purpose:This experiment established successfully EM model of big mouse, monitor the influence of the method of "Fu Zheng Qu Yu " in traditional Chinese medicine to EM model of big mouse by using "ELASE" and other techniques, explore the effect of this method to EM and the advantage of administration through pelvic cavity. Means:In this task, the method of "Fu Zheng Qu Yu " includes oral administration of "Fu Zheng Qu Yu "soup, administration of "Shen Qi Fu Zheng "Injecting liquid through pelvic cavity, and in comparison with oral administration of Western medicine "danazol"1. Basic experimentâ‘  In this task, endometrium shelled out of healthy female Wistar big mouse wassuturedin peritoneum andâ‘¡ Healthy adult female Wistar big mice can be divided randomly into the following groups: Group A (blank group), Group B (model group), Group C (administration of "Fu Zheng Qu Yu "soup), Group D (administration of "Shen Qi Fu Zheng" injecting liquid), Group E (traditional Chinese medicine group, administration of soup and injecting liquid), Group F ("danazol" group) to blood rheology ,immune function and prostaglandin.2. Clinical researchThe patients who suffered from EM was in comparison with oral administration of western medicine "danazol" Accordingly we can inspect the clinical symptom, body trait, pregnancy, CA₁₂₅, EmAb. Result: 1, Animal experiment section(T)The method of "Fu Zheng Qu Yu " can destroy the abnormal endometrium gland of EM model of big mouse,?This method can reduce the content of PGE2 of EM model of big mouse.Compared with GroupB,it has remarkable different (P<0.05). There is no statistical meaning compared GroupE with GroupF and GroupC(P>0.05) .The effects of these three groups are similar. GroupD can reduce PGE2.But the effect not so good as GroupF , GroupE and GroupC (P<0.05).?This method can improve the change of blood rheology of big mouse caused by EM.(P<0.05).GroupC,GroupE compared with GroupF,there is remarkable different(P<0.05).(4)Each treating group can reduce the content of element IL-6 in serum of EM model of big mouse. There is no statistical meaning between Group F and E.(P>0.05)?Each treating group can increase the content of IFN-r. There is no statistical meaning between Group E and F(P>0.05). 2.Clinical Research Section(DThe method of "Fu Zheng Qu Yu"can obviously improve the clinical symptom and body trait of the patients(P>0.05), between Group E and F in cure rate and effective rate of bysmenorrhea.But a half year later,remarkable different (P<0.05)becomes in cure rate, Group E is better than Group F When evaluating short-term curative effect of EM,there is no remarkable difference between Group E and F in cure rate and effect-term curative effect,remarkable difference(P<0.05)becomes in cure rate and effective rate,Group E is better than Group G.Meanwhile,Group E has little side effect.? This method can eliminate the patients'antibody to endometrium and reduce the content of CA125.Compared with Group F it has not statistical meaning (P<0.05).