Study On CM Syndrome And Its Diagnostic Evaluation For Protracted Abstinence Symptom Of Opium-Addicts

Objective Protracted abstinence symptom (PSA ) of opium-addicts is included in the syndrome after cutting the addiction in CM theory. PAS means a series of sustained symptoms following the acute abstinence syndrome, which disappears in 7 to 10 days if without any treatments, consisting psychological symptoms (etc. anxiety, craving for drugs) and physical symptoms (etc. uncomfortableness, sleeping obstacles). In this way, PAS becomes a factor of relapse. Therefore it's a point of intervening relapse from the medical perspective to deal with PAS. At present, there are several Western Medicine treating methods, substitutive treatment of opium drugs, focalized treatment by non-opium drugs and antagonist treatment and focalized treatment by opium drugs. Those have positive effects in releasing symptoms and preventing from reusing dugs, but they also bring out some unhealthy reactions. In the field of treating that kind of illnesses, CM has a comparatively intact theoretical understanding, reliable clinical experience, various treating methods and abundant medicine resource. CM treatments are more and more concerned and its clinical practice and the new medicine development are greatly active. However, because of the shortness of macro-research of regularity on clinical treatments and using medicine based on overall analysis against PAS, standardized diagnostic criterion has not been established, and unified and scientific requirements of observation indexes, curative effect evaluation standards and clinical experiments are insufficient. Nowadays Western Medicine is researching how to scaleulate the quantifying scale on protracted syndromes. But it can't reflect the features of CM and is difficult to direct clinical practice of CM. This topic aims to establish CM syndrome classification and diagnostic criterion, through summarizing the past experience by literature and theory research, launching polycentric and vast-sampled investigations by clinical epidemiological investigation methods, analyzing the investigation and research data by diagnostic evaluation methods. This research not only conscales to the general tendency of standardization development of CM,but also, more or less, can guide the clinical practice and new medicine development of CM against PAS.Methods (1) Documentary research and clinical research: Sort out the data about opium-abstinence systematically from the documents of CM since Qing Dynasty, and make thorough investigations into drug rehabilitation centers, to select out the common syndromes of CM during the protracting period after the abstinence of opium-addiction, and establish the syndrome concepts and diagnostic criterion of CM tentatively. (2) Designing quantifying scale of CM on PAS: The scale should involve 4 items: general data, the inscaleation of symptoms, syndrome classification standard and syndrome evaluation criterion. Then consult to experts for initial evaluating. (3) Pre-experiment: Engage in the narrow-sampled clinical epidemiological experiment, and examine the accuracy, integrity and feasibility of the scale. (4) Revising the scale: Based on the pre-experiment. Consult to experts again and revise the quantifying scale, in order to make the syndrome classification and diagnostic criterion not only accord with the principles of diagnosis and treatment of CM, reflecting the features of CM against PAS, but also be easy to use. (5) Launch polycentric and vast-sampled clinical epidemiological investigation and fill the scale. (6) Make the statistics and analysis on the scale data, to establish the CM syndrome classification and measurable diagnostic criterion, with DME and diagnostic metrological methods.Results (1) Laws of development and basic elements of PAS. Seven basic syndrome elements are heat-toxin syndrome, blood-stagnation syndrome, qi-stagnation syndrome, qi-deficiency syndrome, blood-deficiency syndrome, yang-deficiency syndrome and yin-deficiency syndrome. Referring to the 5 results of an investigation lasting 120 days, heat-toxin syndrome was always at a hig...