| The main experimental parts of this dissertation were carried out in The second affliated hospital of Guangzhou University of TCM, the school of Chinese Materia Medica, Guangzhou University of TCM, and Foshan medical school during the years 1999-2002.I wish to express my deepest gratitude to my supervisor Professor Guo-wei XUAN, for his continuous interest most valuable help, support,comments and tireless encouragement throughout this work.Special thanks are due to Da-Can CFIEN, for his constructive discussion and advice, pleasant cooperation, and for his most valuable help, which made life easier.I would like to express my sincerest gratitude to Professor Zhaoshen HUANG, the head of the school of Chinese Materia Medica, Guangzhou University of TCM . I would like to express my sincerest gratitude to the teachers of The affiliated hospital of Foshan medical school, for their providing excellent research facilities.I am especially grateful to Bao-jian Fan, Ji-wen Zhao, Ning wang from Department of epidemiology, Medical college of DongNan University, for their most valuable help in a variety of aspects, and for their supports, comments and enjoyable cooperation throughout this work.I also owe my thanks to Anping Yang, for his most valuable helps, fruitful discussion and cooperation, and for his introducing me to the field of Chinese material medica.Sincere thanks are due to all the personnel staff and colleagues at Dermatology Department of Guangdong provincial T.C.M hospital, for creating a friendly and helpful working atmosphere. I also wish to extend my warm thanks to all the people at Guangdong provincial T.CM. hospital ,who have helped me in various aspects.I would like to express my deepest thanks to my parents and my brother, my sister for their everlasting love, understanding, support and encouragement they have given me in my life.Clinical And Experimental Studies On Niaoluqing And FuyinkangjieTreatingNongonococcalUrethritis(cervicitis) Caused By CT ABSTRACTPart I General IntroductionNongonococcal urethritis(NGU) is a kind of venereal disease, which is caused by C. Trachomatis(CT),U. Urealyticum(Uu),M. Hominis (Mh), herpes simplex virus II( Hsv2) Candida(Cd), T. Vaginalis (Tv) and other agents. Among them,CT is knownas an important pathogenic factor, and was transmitted through sexual intercourse. Men complain of dysuria and mucoid or mucopurulent urethral discharge, vaginal discharge is perhaps the most common complaint of women. NGU caused by CT has a double importance:first, as a disease which affects the patient locally and generally, by causing fertil and steril ,it may ascend to endometrium and fallopian tubes, by causing salpingitis and other complications; secondly; by causing neonatal pneumonia, or by affecting the child with neonatal infection.Up to 50%of cases of nonspecific urethritis are caused by Chlamydia trachomatis. Chlamydiae are bacterica which require living cell (cell culture) for cultivation. They can be the primary cause of a chronic urethritis or be a concomitant infection in other types of urethritis (especially gonorrhea). Since Halberstadter and von Prowazek, this urethritis has been described as inclusion blennorrhea because inclusion bodies are detectable microscopically in epithelial cells affected by the pathogen on staining with Giemsa. The incubation time may be 4 days to 1 month, and the inflammation is usually limited to the anterior urethra.The chlamydiae can be detected in urethral smears using monoclonal antibodies and fluorescence microscopy. Kits for routine investigations are available Definite proof of Chlamydia trachomatis is based on culture of the organisms on McCoys cells in specialized laboratories and identification using iodine or Giemsa stain or fluorescence-labeled monoclonal antibodies.Tetracycline HCL SOOmg orally 4 times daily, doxycycline lOOmg orally twice daily, or erythromycin SOOmg 4 times daily; all for days.NGU is a part of stranguria with turbid urine (a syndrome marked by dif... |
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